Inovação de alto impacto baseada no conhecimento. A plataforma digital NOVA University Innovation agrega os principais hubs criação de valor.
To raise awareness within the NOVA community concerning the potentials and legal intricacies surrounding intellectual property (IP), the objective of this workshop is to convene those who are closely tied to the software, AI, and computer science domains, as well as others who develop software-based solutions. Special emphasis is placed on scientists, researchers, and both academic and non-academic staff, aiming to impart insights into the significance of IP in their endeavours and projects, while equipping them with fundamental knowledge on the subject.
Additionally, the event aims to clarify NOVA's academic community on its policies and internal procedures, providing valuable insights into best practices and practical tips.
[/et_pb_accordion_item][et_pb_accordion_item title="What's it about?" _builder_version="4.24.0" _module_preset="default" global_colors_info="{}" open="off"]Innovative, passionate, and creative individuals play a fundamental role in propelling progress towards a better and more sustainable future. The safeguarding of intellectual property (IP) becomes paramount in fostering the development of cutting-edge solutions in software and artificial intelligence (AI), with profound societal impacts. Just as in other industries, comprehending the implications and advantages of IP is central in this dynamic field. Intellectual capital thus emerges as a cornerstone in this landscape, underscoring the critical need to grasp the ramifications and benefits of IP.
Within NOVA’s ecosystem, the recognition of impact creation in the software and AI industries is pivotal. To empower researchers and staff in this realm, our workshop delves into the intricacies of IP, offering valuable insights and addressing pertinent questions. Recent technological advancements have birthed innovative tools with diverse applications in software and AI, revolutionizing research paradigms. These advancements usher in novel methods for information exchange among users and developers, along with innovative technical solutions tailored for specific applications.
Throughout the workshop, participants will gain an in-depth understanding of various intellectual property types and their relevance to the software and AI sectors. Practical insights into strategies aimed at safeguarding intellectual property and capitalizing on research outcomes will also be provided.
Real-world case studies and open discussions will allow participants to delve into specific IP challenges faced by academic researchers in the software and AI industries. By the workshop's conclusion, attendees will depart with a heightened appreciation for intellectual property's significance in academic research, armed with practical strategies for safeguarding and commercializing their innovative endeavours.
Participants are invited to bring their own use cases to be discussed.
[/et_pb_accordion_item][et_pb_accordion_item title="When will it happen?" _builder_version="4.24.0" _module_preset="default" global_colors_info="{}" open="off"]
March 6th, 2024 @ NOVA University Lisbon Rectorate (Campolide Campus), from 14h00 to 18h00.
[/et_pb_accordion_item][/et_pb_accordion][et_pb_button button_url="https://surveys.unl.pt/index.php/259666?lang=en" url_new_window="on" button_text="Register here!" button_alignment="center" _builder_version="4.24.0" _module_preset="default" global_colors_info="{}"][/et_pb_button][et_pb_image src="https://novainnovation.unl.pt/wp-content/uploads/2024/01/EN.png" title_text="EN" align="center" _builder_version="4.24.0" _module_preset="default" animation_style="flip" global_colors_info="{}"][/et_pb_image][/et_pb_column][/et_pb_row][/et_pb_section]Method to estimate accurately the position and metrics (length, width, and height) of any target.
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![BACKGROUND The congenital malformations, arthritis, osteoporosis, traumatic accidents, spinal deformities, among others are the basis for need bone and cartilage replacements. The chronic pain, inflammation or discomfort of these diseases translates into a significant impact on patients’ and hospital treatments costs. There is yet no solution that meets the structural and functional requirements of definitive implants. In the case of trauma, for example, treatment often consists of bone joining or even implants in a nonpermanent situation, that is, requiring more than one surgical intervention which causes pain and discomfort to the patient besides the costs involved. Therefore, the development of low cost, durable, compatible and functional solutions is needed. Namely bone substitutes that can be perfectly integrated, morphologically and anatomically biocompatible, with complex structure and a material that mimics native bone and encourages cell migration, proliferation and differentiation. Ideally a bone substitute has original three-dimensional anatomical shape the trabecular zone is dense and has Young’s modulus in the range of 0.01-0.5 GPa and compressive strength values of 4-12 MPa while the cortical region is porous with compressive strength values in the range 130-225 MPa and modulus Young from 3-30GPa. The development of bone implants represents an area of medicine attracting growing interest in recent years. Most used implants are made of noble metals such as titanium. This material, although with good biocompatibility, strength and durability characteristics, faces often body rejection problems. To avoid that, the metal is coated with a biocompatible ceramic material (zirconia, hydroxyapatite, etc.). Despite their good performance, titanium implants have a much higher Young’s modulus than bone, which leads to localized stress phenomena, increase of osteoblast activity and may lead to periprosthetic osteolysis and consequent implant failure. The 3D printing techniques provided opportunities for the development of customized pieces. Ceramics, plastics and metals are all possible to printing in three dimensions by additive or subtractive techniques. In particular subtractive techniques are already used to perform ceramic teeth for dentistry. A piece of dense ceramic material is mechanically dug until the desired form is obtained. However, the dense ceramic implant behaves most likely the metal implants as it doesn’t allow the body fluids to flow through it. Compared to other techniques, the great advantage of pastes extrusion technique is the facility to mimic the graded porosity of implants while a specific design according to patient needs, reaching the mechanical properties close to those of the native bone, as well as their adequate, porosity, permeability to cells, biocompatibility and durability. The goal of the NOVA researchers is to develop low cost production ceramic implants, permanent, conformal and compatible with the specific needs of patients, mimicking resistance and bioactivity. This approach was achieved in preliminary results focused in 3D printed pieces of ceramics powders, achieving mechanical properties in the range of cortical bone, the most demanding in terms of mechanical strength. Indeed, the cortical mechanical resistance values were achieved just printing pieces layer-by-layer with pastes made with inorganic and organic compounds. The required biocompatibility and osteointegration was also tested in-vivo. TECHNOLOGY OVERVIEW The obtained background data show a real possibility to implement this technology in the veterinary area special to horses, dogs and cats in a first phase. This will open then possibilities and verification to further human applications. From left to right: Sample draw; printed samples after sintering for compression test; geometry and dimensions to tension tests; samples geometry for flexure tests. The mechanical strength obtained from axial compression, the tension and the flexure tests are summarized in table 1, where the obtained values are compared to the trabecular and cortical bone values obtained from literature. Comparison of mechanical teste with bone (values from literature).[1][2] Density and porosity compared to bone. The in-vitro tests were made with SAOS 2 cellules tinted for alkaline phosphatase with naphthol AS-MX phosphate and fast red violet and images of cell proliferation obtained for day 5 (left image) and 11 day (right image) of culture are shown in Figure 2. Figure 2: Image of SAOS 2 cells on the top a PIC sample for day 5 (left) and day 11 (right). The graph shows the evolution of cells growth along 9 days. The in-vivo tests were performed in rabbit being implanted two different samples S1 and S2 and the radiography images obtained after 2, 4 and 12 weeks are shown in Figure 3. Figure 3: Image of the implant (left). The graph represents the % of the bone-to-implant contact (BIC) evolution for two different composition samples. There was no adverse response, either local or systemic. No clinical symptoms of exaggerated inflammation, edema or infection were identified. No extensive bone resorption of the surrounding bone tissue is identified STAGE OF DEVELOPMENT The Technology Readiness Level (TRL) is 4. BENEFITS The main advantage of this technology is to allow the printing of a customized bone according to the needs of replacement. It enables the production of bone with gradient of density, in the exterior, properties similar to cortical bone, and, in the interior, density and properties of trabecular bone. Adding to that, the good osteointegration of the material, will allow a giant step towards bone’s mimicking especially for implants in animals, as a first step. Avoiding the need for a second operation for removing metallic parts, or due to rejection problems. APPLICATIONS The potential market is the implants in animals, horses, dogs and cats. There is a huge market for pets, which will allow also to consolidate the technology before it can be implemented in humans. OPPORTUNITY The NOVA team is looking for a co-development partner or a licensee for the implementation of this technology. IP STATUS Know-how based SEEKING Development partner Licensing](https://novainnovation.unl.pt/wp-content/uploads/2021/02/tech_image_2.7ccfbcf1.jpg)
